Mounties responded to a crash on Highway 104 in Havre Boucher last night.
The road is still closed between exit 38 and 39 motorists are asked to use Highway 4 between the two exits.
The crash happened around 9:00 and it involved a transport truck and a car. The truck was heading west towards Antigonish, and the car was headed towards Cape Breton Island.
One person was taken to the hospital by ambulance and their condition is unknown.
